After catching the three Gleason brothers and putting them in their graves with the help of John Bodine and the huge wolf, Shadow, Jess finds himself on the hunt for even more ruthless killers. The hunt takes him to several towns.
When he takes the body of another killer back to the marshal in the town of Salisbury, he meets a fifteen-year-old girl whose father has been murdered by two outlaws. After discovering who the two men are, Jess tells her that he will track them down.
The next morning, when he’s ready to leave Salisbury on the hunt for the two men, he finds the girl already sitting on Sharps In the livery…and she’s not getting off no matter what he says.
Jess is on the trail of the next man on his hunt list, Stacey Kern, when he comes across a strange custom-built and enclosed wagon. The men escorting the wagon try to hire Jess as one of their guards.
He doesn’t accept the job but it seems his travels crisscross the wagon on its way to Houston, Texas. Along the way, he encounters two other outlaws who aren’t wanted dead or alive, but are obviously interested in what’s in the wagon.
He stops the two outlaws from ambushing the wagon, but then they meet up with two other men who have some information about the wagon and what’s being transported inside it.
The four outlaws team up together and attempt another ambush. Jess shows up during the middle of the fight.
Bullets fly and men die.
Jess is back on the hunt for more wanted killers. His search for Lester Donnely takes him to the town of Tobin, where he confronts two drifters who killed one of the town locals. Then, a badly wounded man rides his horse into town. He falls unconscious and drops onto the street.
When the Kirby County sheriff shows up in Tobin, he questions Jess about his killing of the two drifters. Then, he identifies the wounded man as State Supreme Court Justice Chris Meacham.
When United States Marshal Frank Reedy hears about Meacham, he assigns Jess the task of finding the two men who ambushed the Supreme Court justice. Meacham finally comes around and describes the two ambushers in detail. Jess knows exactly who they are.
Reedy sends Bodine to help Jess capture the ambushers to bring them in alive to hang. Things get much more difficult when Jess discovers an unknown shooter is attempting to kill him.
Jess is back on the trail, hunting for Saul Green, when he comes across a cattle ranch run by Loretta McIntire. She offers him a job chasing rustlers off her land, but he turns it down.
While there, he meets a high-priced gun for hire, Raif Wood. He’s looking to get hired on as Loretta’s personal bodyguard. Jess joins them for lunch and then leaves to go back on the hunt for Green.
When he takes Green’s body to the town of Clinton to turn in to the law for the bounty, he discovers that Lorretta has been brutally murdered and Raif Wood took a bullet in his shoulder trying to protect her.
Jess goes after the four killers and Wood goes along with him even though he’s wounded. Once that problem is resolved, he happens upon another tragedy and meets a man by the name of Jimmy.
Another hunt begins, but it doesn’t end the way Jess thought it would.