Jess is tracking a murderous monster, Mark Milton, through the state of Texas, but he keeps slipping through his fingers and leaving a trail of dead bodies behind.
Things get more complicated when an unknown foe starts sending men to kill Jess, making his job of catching up to Milton more dangerous. As he hunts down the madman, he uncovers a plan to have him murdered, but still has no idea of who is behind it.
By the time he finally kills Milton, he has information that will take him to St. Louis, Missouri, where he finds help from some old friends. They unravel the entire plot, Jess ends it in his usual manner. He then sets out with his friends to finish a hunt for a man in New Mexico Territory.